Christian Louboutin non-responding patients

Frequent grade 3-4 adverse events were neutropaenia (81.6%), Wedding Shoes on Sale (19.7%), febrile neutropaenia (19.7%), anaemia (15.5%) and pain (9.9%). We did not observe confirmed objective responses. All cohorts were closed Cheap Christian Louboutin Boots the entry of 14-15 eligible non-responding patients. Pharmacokinetic analyses revealed multi-compartmental behaviour and a rapid distribution of BI 2536. "BI 2536 is a selective and potent small-molecule inhibitor of polo-like kinase 1 (see also Breast Cancer). We performed a multi-centre, multi-tumour phase II trial to investigate the efficacy, safety and pharmacokinetics of BI 2536 in five solid tumour types. Patients with advanced head and neck, breast and ovarian cancer, soft tissue sarcoma and melanoma were selected according to protocol-defined general and tumour-Cheap Christian Louboutin Boots criteria," researchers in Louvain, Belgium report. "They were >= 18 years old, had a good performance status, adequate bone marrow, renal and liver function, measurable progressive disease and had completed other relevant systemic treatments >4 weeks ago. BI 2536 200-250 mg was given intravenously Cheap Christian Louboutin Boots day 1 every 3 weeks until intolerance, progression or refusal.

Par baixue le samedi 23 octobre 2010

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